Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 Integrase Inhibitors That Are Active against Drug-Resistant Integrase Mutants

29 Jun 2020

Abstract excerpt

Thus, it is important to develop new and improved INSTIs that are effective against all the known resistant mutants. This led us to test our best inhibitors, in parallel with DTG, BIC, and CAB, in a single-round infection assay against a panel of the new CAB-resistant mutants. Of the INSTIs we tested, BIC and our compound 4d had the broadest efficacy. Both were superior to DTG, as evidenced by the data obtained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical and Molecular Research
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32601157
DOI: 10.1128/aac.00611-20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 Integrase Inhibitors That Are Active against Drug-Resistant Integrase MutantsPMID 32601157Read ↗

HIV-1 Integrase Inhibitors That Are Broadly Effective against Drug-Resistant Mutants.Semantic proximity Read ↗

Efficacies of Cabotegravir and Bictegravir against drug-resistant HIV-1 integrase mutants.Semantic proximity Read ↗

Anti-HIV-1 Activity of the Integrase Strand Transfer Inhibitor ACC017.Semantic proximity Read ↗

Antiviral Activity of Bictegravir and Cabotegravir against Integrase Inhibitor-Resistant SIVmac239 and HIV-1.Semantic proximity Read ↗

HIV-1 integrase strand transfer inhibitors: a review of current drugs, recent advances and drug resistanceSemantic proximity Read ↗

Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs.Semantic proximity Read ↗

4-amino-1-hydroxy-2-oxo-1,8-naphthyridine-containing compounds having high potency against raltegravir-resistant integrase mutants of HIV-1.Semantic proximity Read ↗

HIV drug resistance against strand transfer integrase inhibitors.Semantic proximity Read ↗

Integrase strand transfer inhibitor (INSTI)-resistance mutations for the surveillance of transmitted HIV-1 drug resistanceSemantic proximity Read ↗

Prevalence of Integrase Strand Transfer Inhibitors Resistance Mutations in Integrase Strand Transfer Inhibitors-Naive and -Experienced HIV-1 Infected Patients: A Single Center Experience.Semantic proximity Read ↗

Bicyclic 1-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-containing HIV-1 integrase inhibitors having high antiviral potency against cells harboring raltegravir-resistant integrase mutants.Semantic proximity Read ↗

Selection and analysis of HIV-1 integrase strand transfer inhibitor resistant mutant viruses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.