Article
The E. coli recA gene can restore the defect in mutagenesis of the pso4-1 mutant of S. cerevisiae.
Mutation research - 1 May 1994
Morais Júnior M A, Brozmanová J, Benfato M S, Duraj J, Vlcková V, Henriques J A
Abstract excerpt
The E. coli recA gene was introduced into the pso4-1 mutant of S. cerevisiae and transformants were treated with 8-MOP+UVA and 254-nm UV light. The results showed that the recA gene increased the resistance to the toxic effect of 8-MOP+UVA and restored the frequency of reversion of the pso4-1 mutants after both treatments. The presence of the recA gene stimulated expression of the small subunit of the...
Topics
- DNA Repair
- Epistasis, Genetic
- Escherichia coli
- Genes, Bacterial
- Genes, Fungal
- Methoxsalen
- Mutagenesis
- Mutation
- Rec A Recombinases
- Saccharomyces cerevisiae
- Transformation, Genetic