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Article

Effects of bleomycin on growth kinetics and survival of Saccharomyces cerevisiae: a model of repair pathways.

Journal of bacteriology - 1 May 1992

Keszenman D J, Salvo V A, Nunes E

Abstract excerpt

In order to analyze the roles of some repair genes in the processing of bleomycin-induced DNA damage and, especially, the interrelationships among the involved repair pathways, we investigated the potentially lethal effect of bleomycin on radiosensitive mutants of Saccharomyces cerevisiae defective in recombination, excision, and RAD6-dependent DNA repair. Using single, double, and triple rad mutants, we analyzed...

Topics

Bleomycin
Cell Division
DNA Damage
DNA Repair
DNA Replication
Dose-Response Relationship, Drug
Epistasis, Genetic
Models, Biological
Mutation
Radiation Tolerance
Recombination, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

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Open in PubMed Open full text

Identifiers

PMID: 1374375
DOI: 10.1128/jb.174.10.3125-3132.1992
PMCID: PMC205977

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1374375-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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