Mouse dominant lethal and sperm abnormality studies with combined exposure to X-rays and mitomycin C.

doi:10.1016/0027-5107(94)90032-9

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Article

Mouse dominant lethal and sperm abnormality studies with combined exposure to X-rays and mitomycin C.

Mutation research - 15 Apr 1994

Dobrzyńska M M, Gajewski A K

Abstract excerpt

The induction of dominant lethal effects and sperm abnormalities in Pzh:Swiss male mice after treatments with X-rays and mitomycin C (MMC) was investigated. Combinations of high (1.00 Gy + 5.25 mg/kg bw MMC) and low (0.25 Gy + 1.75 mg/kg bw MMC) doses of both agents were used. Exposure to high do...

Topics

Animals
Male
Mice
Mitomycin
Mutagenicity Tests
Mutation
Spermatozoa
X-Rays

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