Article
Cytogenetic characterization of radiosensitive mouse mutants.
Mutation research - 1 Dec 1991
van Buul P P, Tuinenburg-Bol Raap A, Goudzwaard H J, Seelen C M, Beechey C V, Natarajan A T, Searle A G
Abstract excerpt
In order to develop mouse models for human mutagen-sensitive syndromes, we carried out cytogenetic characterization of several mouse mutants and MS/Ae mice showing enhanced radiosensitivities. The applied cytogenetic techniques include chromosomal analysis of in vitro cell cultures and lymphocyte...
Topics
- Animals
- Bone Marrow
- Bone Marrow Cells
- Cells, Cultured
- Chromosome Aberrations
- Chromosomes
- DNA
- Female
- Genotype
- Liver
- Male
- Mice
- Mice, Mutant Strains
- Radiation Tolerance
- Testis