Article
Cytogenetic characterization of radiosensitive mouse mutants.
Mutation research - 1 Dec 1991
van Buul P P, Tuinenburg-Bol Raap A, Goudzwaard H J, Seelen C M, Beechey C V, Natarajan A T, Searle A G
Abstract excerpt
In order to develop mouse models for human mutagen-sensitive syndromes, we carried out cytogenetic characterization of several mouse mutants and MS/Ae mice showing enhanced radiosensitivities. The applied cytogenetic techniques include chromosomal analysis of in vitro cell cultures and lymphocyte cultures as well as in vivo UDS in hepatocytes, induction of micronuclei in polychromatic erythrocytes and...
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