Evaluation of spermatogenic response of mice to the induction of mutations by combined treatment with X rays and antineoplastic drugs.

doi:10.1007/BF01212678

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Article

Evaluation of spermatogenic response of mice to the induction of mutations by combined treatment with X rays and antineoplastic drugs.

Radiation and environmental biophysics - 1 Jan 1994

Lenarczyk M, Dobrzyńska M, Słowikowska M G, Gajewski A K

Abstract excerpt

Combined treatment with low doses of X-rays plus cyclophosphamide (0.25 Gy + 25 mg/kg body weight) or X-rays plus mitomycin C (0.25 Gy + 1.75 mg/kg body weight) did not induce significant dominant lethal effects in any stage of spermatogenesis when a parameter representing pre- and postimplantati...

Topics

Animals
Cyclophosphamide
Female
Male
Mice
Mitomycin
Mutation
Spermatogenesis
X-Rays

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