Article
Induction of dominant lethal mutations by combined X-ray-acrylamide treatment in male mice.
Mutation research - 1 Oct 1990
Dobrzyńska M, Lenarczyk M, Gajewski A K
Abstract excerpt
The induction of mutations following combined treatment with acrylamide (AA) plus X-rays has been determined using the dominant lethal mutations test in Pzh:SFISS male mice. Combinations of a mutagenic dose of both agents (1.00 Gy, 125 mg/kg b.w.) and a non-mutagenic dose, i.e., a dose that alone does not produce dominant lethals (0.25 Gy, 25 mg/kg b.w.), were used. For the discussion of the effects of combined...
Topics
- Acrylamide
- Acrylamides
- Animals
- Female
- Genes, Dominant
- Genes, Lethal
- Male
- Mice
- Mutation
- Pregnancy
- X-Rays