Article
Acrolein genotoxicity in Drosophila melanogaster. II. Influence of mus201 and mus308 mutations.
Mutation research - 1 Apr 1994
Barros A R, Comendador M A, Sierra L M
Abstract excerpt
The influence of mus201 and mus308 mutants on acrolein mutagenicity was analyzed with the Drosophila melanogaster sex-linked recessive lethal test (SLRL), using the maternal approach, to further study the mechanisms of action of this chemical. The hypermutability indices obtained were 2.59 for mus201 and 0.52 for mus308 conditions. Statistical analysis indicates that whereas part of the acrolein-induced lesions...
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