Article
[Comparative analysis of the "Meller-5" and somatic mosaicism methods with relation to the activity of standard mutagens].
Farmakologiia i toksikologiia - 1 Jan 2000
Belova L L, Durnev A D, Seredenin S B
Abstract excerpt
The study of the genotoxic activity of ethidium bromide and bleomycin by the two methods in Drosophila melanogaster showed that both drugs possess the mutagenic activity. The comparison of the data obtained for both drugs by the methods of recessive, sex-linked, lethal mutations and somatic mosai...
Topics
- Animals
- Bleomycin
- Dose-Response Relationship, Drug
- Drosophila melanogaster
- Ethidium
- Evaluation Studies as Topic
- Female
- Genes, Lethal
- Genes, Recessive
- Genetic Linkage
- Male
- Mosaicism
- Mutagenicity Tests
- Mutagens
- Mutation