Article
[Analysis of the mutagenic and teratogenic effect of griseofulvin in the mutagen-sensitive Drosophila melanogaster line mus(2)201G1].
Genetika - 1 Jun 1994
Isaenko O A, Romashkina T B, Shvartsman P Ia, Shelomova L F
Abstract excerpt
The mutagenic effect of griseofulvin was demonstrated in a wing somatic mosaicism test (SMART) in different Drosophila lines. The mutagenic effect of this agent is accompanied by a pronounced toxic effect on Drosophila larvae and by a teratogenic effect, which is manifested in the reduction of om...
Topics
- Animals
- Drosophila melanogaster
- Female
- Genotype
- Griseofulvin
- Male
- Mosaicism
- Mutagens
- Mutation
- Teratogens