Article
[The specificity of the genotoxic action of carcinogenic aromatic compounds on Drosophila mus mutants].
Biulleten' eksperimental'noi biologii i meditsiny - 1 Nov 1991
Shpigel'man V S, Fuks S Iu, Safaev R D, Belitskiĭ G A
Abstract excerpt
Hypersensitivity to the toxic effect of benzo(a)pyrene (B(a)P) was determined in homozygous larvae of two D. melanogaster mus strains (mus 208B2 and mus210). The two others (mus205B1 and mus208B1) were found to be less sensitive and the parent strain was resistant. The lack of correlation between the sensitivity in larvae and the activity of aryl hydrocarbon hydroxylase in S15 fractions from adult flies whole...
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