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Article

Acrylamide is genotoxic to the somatic and germ cells of Drosophila melanogaster.

Mutation research - 1 Jan 1991

Tripathy N K, Patnaik K K, Nabi M J

Abstract excerpt

The genotoxic effects of acrylamide, a recently detected carcinogen, have been studied in the somatic (wing primordia) and germ cells of Drosophila melanogaster by the wing mosaic assay and the sex-linked recessive lethal test respectively. Larvae, 72 +/- 4 h old, were exposed to 6 different concentrations of acrylamide ranging between 0.25 mM and 5.0 mM in instant medium for 48 h. It is observed that acrylamide...

Topics

Acrylamide
Acrylamides
Animals
Drosophila melanogaster
Female
Genes, Lethal
Genes, Recessive
Germ Cells
Male
Mosaicism
Mutagenicity Tests
Mutation

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Identifiers

PMID: 1899131
DOI: 10.1016/0165-1218(91)90105-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1899131-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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