Article
Expression of CD44 in human lung tumors.
Cancer research - 1 Mar 1994
Penno M B, August J T, Baylin S B, Mabry M, Linnoila R I, Lee V S, Croteau D, Yang X L, Rosada C
Abstract excerpt
CD44 is an integral membrane glycoprotein that functions as a receptor for the extracellular matrix glycan, hyaluronan. Here we report that CD44 is a novel biomarker for non-small cell lung tumors, squamous metaplasia of the lung, and activated type II pneumocytes. We have examined the expression of CD44 in 12 human lung tumor cell lines and 23 fixed, paraffin-embedded lung cancers. CD44 transcription and...
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