Article
Expression of CD44 in human lung tumors.
Cancer research - 1 Mar 1994
Penno M B, August J T, Baylin S B, Mabry M, Linnoila R I, Lee V S, Croteau D, Yang X L, Rosada C
Abstract excerpt
CD44 is an integral membrane glycoprotein that functions as a receptor for the extracellular matrix glycan, hyaluronan. Here we report that CD44 is a novel biomarker for non-small cell lung tumors, squamous metaplasia of the lung, and activated type II pneumocytes. We have examined the expression...
Topics
- Antigens, Surface
- Base Sequence
- Biomarkers, Tumor
- Bronchi
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Carrier Proteins
- Epithelium
- Genes, ras
- Humans
- Hyaluronan Receptors
- Lung
- Lung Neoplasms
- Metaplasia
- Molecular Sequence Data
- Phenotype
- RNA Splicing
- RNA, Messenger