Article
Isoform expression of CD44 adhesion molecules, Bcl-2, p53 and Ki-67 proteins in lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2000
Mizera-Nyczak E, Dyszkiewicz W, Heider K H, Zeromski J
Abstract excerpt
CD44, belongs to the cell adhesion molecule family and is expressed on cell surfaces in several isoforms which are generated by alternative splicing of messenger RNA. These splice variants have been shown in several cancer cell types and are thought to be involved in tumor progression. The aim of the current study was to evaluate the expression of selected CD44 variants on lung cancer cells of various histology...
Topics
- Adenocarcinoma
- Adult
- Aged
- Alternative Splicing
- Antibodies, Monoclonal
- Apoptosis
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cell Differentiation
- Disease Progression
- Female