Article
Expression of CD44 splice variants during lymphocyte activation and tumor progression.
Cell adhesion and communication - 1 Jul 1994
Griffioen A W, Horst E, Heider K H, Wielenga V J, Adolf G R, Herrlich P, Pals S T
Abstract excerpt
Recently, splice variants of CD44 have been described that confer metastatic potential to non-metastasizing rat pancreatic carcinoma and sarcoma cell lines. Using antibodies against variant CD44 (CD44v) sequences, we have examined the expression of variant CD44 glycoproteins on human lymphoid cells and tissues and in colorectal neoplasia. Lymphohematopoietic cells express low levels of CD44v glycoproteins. During...
Topics
- Alternative Splicing
- Animals
- Biomarkers, Tumor
- Carrier Proteins
- Colorectal Neoplasms
- Genetic Variation
- Humans
- Hyaluronan Receptors
- Immunohistochemistry
- Lymphocyte Activation
- Prognosis
