Article
CD44 expression in colorectal adenomas is an early event occurring prior to K-ras and p53 gene mutation.
Archives of biochemistry and biophysics - 1 May 1994
Kim H, Yang X L, Rosada C, Hamilton S R, August J T
Abstract excerpt
Neoplastic progression of colorectal epithelial cells from benign adenomas to malignant carcinomas appears to result from a series of genetic alterations involving both oncogenes and tumor suppressor genes. This progression was recently found to be associated with expression of splice variant iso...
Topics
- Adenoma
- Base Sequence
- Biomarkers, Tumor
- Blotting, Western
- Carrier Proteins
- Cell Transformation, Neoplastic
- Codon
- Colorectal Neoplasms
- Gene Expression
- Genes, p53
- Genes, ras
- Humans
- Hyaluronan Receptors
- Mutation
- Neoplasm Staging
- Point Mutation
- Receptors, Cell Surface
- Receptors, Lymphocyte Homing