Article
Molecular genetic characterization of alternatively spliced CD44 transcripts in human stomach carcinoma.
Journal of Korean medical science - 1 Dec 1997
Kim Y S, Chi S G, Kim Y W, Park Y K, Yoon C
Abstract excerpt
CD44 is a member of cell surface glycoproteins which are involved in cell-matrix adhesion and tumor metastasis. Certain types of tumors express complex CD44 isoforms generated by alternative splicing of 2v-10v exons, and their expression appears to promote metastasis of tumor cells. Using a neste...
Topics
- Adult
- Age Factors
- Alternative Splicing
- DNA, Complementary
- Disease Progression
- Exons
- Female
- Gene Expression
- Genetic Variation
- Glyceraldehyde-3-Phosphate Dehydrogenases
- Humans
- Hyaluronan Receptors
