Article
Molecular genetic characterization of alternatively spliced CD44 transcripts in human stomach carcinoma.
Journal of Korean medical science - 1 Dec 1997
Kim Y S, Chi S G, Kim Y W, Park Y K, Yoon C
Abstract excerpt
CD44 is a member of cell surface glycoproteins which are involved in cell-matrix adhesion and tumor metastasis. Certain types of tumors express complex CD44 isoforms generated by alternative splicing of 2v-10v exons, and their expression appears to promote metastasis of tumor cells. Using a nested RT-PCR, we analyzed expression of CD44 variants in 26 stomach carcinoma, 21 matched normal tissues, and 2 carcinoma...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
