Article
c-kit ligand combined with GM-CSF and/or IL-3 can expand CD34+ hematopoietic progenitor subsets for several weeks in vitro.
Stem cells (Dayton, Ohio) - 1 Mar 1994
Steen R, Mørkrid L, Tjønnfjord G E, Egeland T
Abstract excerpt
It might be possible to facilitate engraftment after transplantation of purified hematopoietic progenitor cells if the cells are stimulated ex vivo prior to transplantation. The aim of this study was to analyze the potential of c-kit ligand (CKL) combined with granulocyte-macrophage colony-stimul...
Topics
- Adult
- Antigens, CD
- Antigens, CD34
- Cell Differentiation
- Cell Division
- Cells, Cultured
- Flow Cytometry
- Granulocyte-Macrophage Colony-Stimulating Factor
- Hematopoietic Cell Growth Factors
- Hematopoietic Stem Cells
- Humans
- Interleukin-3
- Ligands
- Phenotype
- Stem Cell Factor