Article
B cell contribution of the CD4+ T cell inflammatory phenotypes in systemic lupus erythematosus.
Autoimmunity - 1 Feb 2017
Choi Seung-Chul, Morel Laurence
Abstract excerpt
Systemic lupus erythematosus is an autoimmune disease in which the effector molecules responsible for tissue damage are antibodies directed against a large number of self-antigens, among which nucleic acids complexed with proteins play a prominent role. These pathogenic autoantibodies are produced by plasma cells differentiated from activated autoreactive B cells, a process that requires complex interactions...
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