Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases.

doi:10.1083/jcb.124.3.351

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases.

The Journal of cell biology - 1 Feb 1994

Cunningham K W, Fink G R

Abstract excerpt

Ca2+ ATPases deplete the cytosol of Ca2+ ions and are crucial to cellular Ca2+ homeostasis. The PMC1 gene of Saccharomyces cerevisiae encodes a vacuole membrane protein that is 40% identical to the plasma membrane Ca2+ ATPases (PMCAs) of mammalian cells. Mutants lacking PMC1 grow well in standard...

Topics

Amino Acid Sequence
Base Sequence
Calcineurin
Calcium
Calcium-Transporting ATPases
Calmodulin
Calmodulin-Binding Proteins
Cell Membrane
Cloning, Molecular
Cyclosporine
Enzyme Activation
Fungal Proteins
Genes, Fungal
Molecular Sequence Data
Mutation
Phosphoprotein Phosphatases
Plasma Membrane Calcium-Transporting ATPases
Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 7507493
DOI: 10.1083/jcb.124.3.351
PMCID: PMC2119937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7507493-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics