Article
pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast.
The EMBO journal - 2 Jan 1998
Sugiura R, Toda T, Shuntoh H, Yanagida M, Kuno T
Abstract excerpt
Calcineurin is a highly conserved and ubiquitously expressed Ca2+- and calmodulin-dependent protein phosphatase. The in vivo role of calcineurin, however, is not fully understood. Here, we show that disruption of the calcineurin gene (ppb1(+)) in fission yeast results in a drastic chloride ion (C...
Topics
- Amino Acid Sequence
- Calcineurin
- Calcium-Calmodulin-Dependent Protein Kinases
- Chlorides
- Dual Specificity Phosphatase 1
- Fungal Proteins
- Genes, Suppressor
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Phenotype
- Protein Tyrosine Phosphatases
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins
- Sequence Homology, Amino Acid
- Signal Transduction
