Article
Retrieval and amplification of DNA from unstained histopathological sections.
Biomedical and environmental sciences : BES - 1 Sept 1993
Montague D C, Lyn-Cook B D, Chowdhury P, Chang L W
Abstract excerpt
Testing of compounds for carcinogenic potential in vivo involves various experimental designs. A few of these techniques are directed to demonstrate the genotoxicity and mutagenicity of the compound by histopathology. These changes shown by histochemical means include monoclonal antibody directed...
Topics
- Antibodies, Monoclonal
- DNA, Neoplasm
- Formaldehyde
- Genes, ras
- Histological Techniques
- Mutation
- Paraffin Embedding
- Polymerase Chain Reaction
- Proto-Oncogene Proteins p21(ras)
- Staining and Labeling