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Article

Modulation of the neurofibromatosis type 1 gene product, neurofibromin, during Schwann cell differentiation.

Journal of neuroscience research - 1 Oct 1993

Gutmann D H, Tennekoon G I, Cole J L, Collins F S, Rutkowski J L

Abstract excerpt

Neurofibromin, the product of the neurofibromatosis type 1 (NF1) gene, is a approximately 250 kDa protein expressed predominantly in cortical neurons and oligodendrocytes in the central nervous system (CNS) and sensory neurons and Schwann cells in the peripheral nervous system (PNS). To gain insight into the biological role of neurofibromin in Schwann cells, the modulation of NF1 gene expression in a Schwann cell...

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PMID: 7505343
DOI: 10.1002/jnr.490360212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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