Lack of binding of peptides carrying the human platelet antigen 1 (HPA-1) dimorphism to purified HLA-DRw52a molecules.

doi:10.1016/s1140-4639(05)80156-x

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Article

Lack of binding of peptides carrying the human platelet antigen 1 (HPA-1) dimorphism to purified HLA-DRw52a molecules.

Revue francaise de transfusion et d'hemobiologie : bulletin de la Societe nationale de transfusion sanguine - 1 Oct 1993

Braud V, Valentin N, Choppin J, Cesbron A, Bignon J D, Blanchard D, Muller J Y

Abstract excerpt

The strong association between anti-HPA-1a alloimmunization and DR3, DRw52a phenotype in HPA-1b homozygous women suggests that these class II molecules play a crucial role in the immune response against HPA-1a. The diallelic system HPA-1 results in a single amino acid polymorphism at the residue 33 of the glycoprotein IIIa. So, we tested the binding of peptides from the 25-42 region of the GPIIIa to purified...

Topics

Amino Acid Sequence
Antigens, CD
Antigens, Human Platelet
CD36 Antigens
Chromatography, Gel
Female
HLA-DR Antigens
HLA-DR Serological Subtypes
Humans
Immunization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant, Newborn

Integrin beta3

Molecular Sequence Data

Peptide Fragments

Phenotype

Polymorphism, Genetic

Pregnancy

Protein Binding

Source

Open in PubMed

Identifiers

PMID: 7505078
DOI: 10.1016/s1140-4639(05)80156-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7505078-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Lack of binding of peptides carrying the human platelet antigen 1 (HPA-1) dimorphism to purified HLA-DRw52a molecules.PMID 7505078Read ↗

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