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Extensive genetic alterations in prostate cancer revealed by dual PCR and FISH analysis.

Genes, chromosomes & cancer - 1 Oct 1993

Macoska J A, Micale M A, Sakr W A, Benson P D, Wolman S R

Abstract excerpt

The genetic alterations that underlie prostate tumorigenesis are assumed to comprise gain or loss of specific chromosomal regions, whole chromosomes, or sequence-specific mutations. Existing data have not demonstrated clear specificity of whole chromosome or regional chromosomal gain or loss that characterizes entire individual malignant lesions, or all malignant lesions, within a cancerous prostate. We have...

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PMID: 7504522
DOI: 10.1002/gcc.2870080205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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