Article
Extensive genetic alterations in prostate cancer revealed by dual PCR and FISH analysis.
Genes, chromosomes & cancer - 1 Oct 1993
Macoska J A, Micale M A, Sakr W A, Benson P D, Wolman S R
Abstract excerpt
The genetic alterations that underlie prostate tumorigenesis are assumed to comprise gain or loss of specific chromosomal regions, whole chromosomes, or sequence-specific mutations. Existing data have not demonstrated clear specificity of whole chromosome or regional chromosomal gain or loss that...
Topics
- Base Sequence
- Chromosome Aberrations
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 4
- Chromosomes, Human, Pair 7
- Chromosomes, Human, Pair 8
- DNA Primers
- DNA, Neoplasm
- Humans
- In Situ Hybridization, Fluorescence
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Prostatic Neoplasms
- Y Chromosome