Article
Fluorescence in situ hybridization analysis of 8p allelic loss and chromosome 8 instability in human prostate cancer.
Cancer research - 15 Jul 1994
Macoska J A, Trybus T M, Sakr W A, Wolf M C, Benson P D, Powell I J, Pontes J E
Abstract excerpt
Cytogenetic and molecular biological studies have demonstrated deletion of sequences that map to the short arm of chromosome 8 (8p) in tumors from several organ systems, including sequences that map within or near 8p22 in human prostate tumors. Recent studies in our laboratory have suggested that deletion of sequences on 8p may be concurrent with alterations in dosage for chromosome 8. In order to further...
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