Article
Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen.
Lancet (London, England) - 16 Dec 1995
Bloemenkamp K W, Rosendaal F R, Helmerhorst F M, Büller H R, Vandenbroucke J P
Abstract excerpt
Recent concern about the safety of combined oral contraceptives (OCs) with third-generation progestagens prompted an examination of data from a population-based case-control study (Leiden Thrombophilia Study). We compared the risk of deep-vein thrombosis (DVT) during use of the newest OCs, containing a third-generation progestagen, with the risk of "older" products. We also investigated the influence of family...
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