Article
Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen.
Lancet (London, England) - 16 Dec 1995
Bloemenkamp K W, Rosendaal F R, Helmerhorst F M, Büller H R, Vandenbroucke J P
Abstract excerpt
Recent concern about the safety of combined oral contraceptives (OCs) with third-generation progestagens prompted an examination of data from a population-based case-control study (Leiden Thrombophilia Study). We compared the risk of deep-vein thrombosis (DVT) during use of the newest OCs, contai...
Topics
- Adolescent
- Adult
- Contraceptives, Oral, Combined
- Desogestrel
- Ethinyl Estradiol
- Factor V
- Female
- Humans
- Middle Aged
- Mutation
- Progestins
- Risk Factors
- Thrombophlebitis