Article
The joint effect of genetic risk factors and different types of combined oral contraceptives on venous thrombosis risk.
British journal of haematology - 1 Oct 2020
Khialani Deeksha, le Cessie Saskia, Lijfering Willem M, Cannegieter Suzanne C, Rosendaal Frits R, van Hylckama Vlieg Astrid
Abstract excerpt
It is not known whether the synergistic effect of genetic markers, increasing the risk of venous thrombosis (VT), and combined oral contraceptives (COC) use varies between different types of progestogens in these preparations. We investigated the joint effect of genetic risk factor, that is, F5 rs6025, F2 rs1799963, and FGG rs2066865 mutations, and different progestogens on the risk of VT. The constrained maximum...
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