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Article

Combined oral contraceptives, thrombophilia and the risk of venous thromboembolism: a systematic review and meta-analysis.

Journal of thrombosis and haemostasis : JTH - 1 Jul 2016

van Vlijmen E F W, Wiewel-Verschueren S, Monster T B M, Meijer K

Abstract excerpt

UNLABELLED: Essentials We performed a meta-analysis on thrombosis risk in thrombophilic oral contraceptive (COC)-users. The results support discouraging COC-use in women with a natural anticoagulant deficiency. Contrary, additive risk of factor V Leiden (FVL) or prothrombin-G20210A (PT) mutation is modest. Women with a FVL/PT-mutation as single risk factor can use COCs if alternatives are not tolerated. SUMMARY:...

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Source

Identifiers

PMID: 27121914
DOI: 10.1111/jth.13349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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