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Article

Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation.

Lancet (London, England) - 26 Nov 1994

Vandenbroucke J P, Koster T, Briët E, Reitsma P H, Bertina R M, Rosendaal F R

Abstract excerpt

We investigated whether the occurrence of venous thrombosis in young women who use oral contraceptives might be explained by the factor V Leiden mutation, which leads to resistance to activated protein C and enhances susceptibility to thrombosis. We compared 155 consecutive premenopausal women, aged 15 to 49, who had developed deep venous thrombosis in the absence of other underlying diseases, with 169 population...

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PMID: 7968118
DOI: 10.1016/s0140-6736(94)90286-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation.PMID 7968118Read ↗

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