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Article

Sirt1, p53, and p38(MAPK) are crucial regulators of detrimental phenotypes of embryonic stem cells with Max expression ablation.

Stem cells (Dayton, Ohio) - 1 Aug 2012

Hishida Tomoaki, Nozaki Yuriko, Nakachi Yutaka, Mizuno Yosuke, Iseki Hiroyoshi, Katano Miyuki, Kamon Masayoshi, Hirasaki Masataka, Nishimoto Masazumi, Okazaki Yasushi, Okuda Akihiko

Abstract excerpt

c-Myc participates in diverse cellular processes including cell cycle control, tumorigenic transformation, and reprogramming of somatic cells to induced pluripotent cells. c-Myc is also an important regulator of self-renewal and pluripotency of embryonic stem cells (ESCs). We recently demonstrate...

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Identifiers

PMID: 22696478
DOI: 10.1002/stem.1147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22696478-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Sirt1, p53, and p38(MAPK) are crucial regulators of detrimental phenotypes of embryonic stem cells with Max expression ablation.PMID 22696478Read ↗

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