Variability in DNA repair and individual susceptibility to genotoxins.

Article

Variability in DNA repair and individual susceptibility to genotoxins.

Clinical chemistry - 1 Dec 1995

Kyrtopoulos S A

Abstract excerpt

DNA repair is an important mechanism of cellular protection from the effects of genotoxic chemicals. Although extensive evidence from studies in experimental systems indicates that variation in DNA repair can significantly influence susceptibility to genotoxins, corresponding studies in human pop...

Topics

Animals
Antineoplastic Agents, Alkylating
DNA
DNA Repair
Environmental Exposure
Genetic Predisposition to Disease
Guanine
Hodgkin Disease
Humans
Melanoma
Methyltransferases
Mutagens
O(6)-Methylguanine-DNA Methyltransferase

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