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Article

Improved bactericidal activity of Q-35 against quinolone-resistant staphylococci.

Antimicrobial agents and chemotherapy - 1 Jul 1995

Ito T, Matsumoto M, Nishino T

Abstract excerpt

The bactericidal effects of Q-35, sparfloxacin, tosufloxacin, and ofloxacin on 18 strains of methicillin-resistant Staphylococcus aureus (MRSA) and 3 strains of Staphylococcus epidermidis were studied by a viable-count method. Staphylococci as used in this study were clearly divided into two groups with respect to their susceptibilities to sparfloxacin. MICs of Q-35 and tosufloxacin were 0.05 to 0.78 microgram/ml...

Topics

Anti-Infective Agents
Base Sequence
DNA Gyrase
DNA Topoisomerases, Type II
Fluoroquinolones
Methicillin Resistance
Microbial Sensitivity Tests
Molecular Sequence Data
Mutation
Quinolones
Staphylococcus aureus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Staphylococcus epidermidis

Source

Open in PubMed Open full text

Identifiers

PMID: 7492097
DOI: 10.1128/AAC.39.7.1522
PMCID: PMC162774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7492097-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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