Article
Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.
Antimicrobial agents and chemotherapy - 1 Apr 1993
Yoshida T, Mitsuhashi S
Abstract excerpt
The in vitro antibacterial activity of NM394 was compared with those of other new quinolones. NM394 showed potent and broad-spectrum antibacterial activity against 2,606 recent clinical isolates. The activity of NM394 against gram-positive bacteria was 2- to 16-fold less than that of tosulfoxacin and sparfloxacin but was comparable to that of ofloxacin. Only against Streptococcus pyogenes was the activity of...
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