Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.

doi:10.1128/AAC.37.4.793

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Article

Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone.

Antimicrobial agents and chemotherapy - 1 Apr 1993

Yoshida T, Mitsuhashi S

Abstract excerpt

The in vitro antibacterial activity of NM394 was compared with those of other new quinolones. NM394 showed potent and broad-spectrum antibacterial activity against 2,606 recent clinical isolates. The activity of NM394 against gram-positive bacteria was 2- to 16-fold less than that of tosulfoxacin...

Topics

Anti-Infective Agents
Bacteria
Ciprofloxacin
Dioxolanes
Enoxacin
Fluoroquinolones
Microbial Sensitivity Tests
Mutation
Naphthyridines
Ofloxacin
Piperazines
Quinolones
Topoisomerase II Inhibitors

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