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Article

Identification and genetic definition of a bovine papillomavirus type 1 E7 protein and absence of a low-copy-number phenotype exhibited by E5, E6, or E7 viral mutants.

Journal of virology - 1 Aug 1992

Jareborg N, Alderborn A, Burnett S

Abstract excerpt

The bovine papillomavirus type 1 (BPV-1) genome replicates as a multiple-copy plasmid in murine C127 cells transformed to neoplasia by virus infection or by transfection with BPV-1 DNA. It was reported previously that BPV-1 genomes harboring frameshift mutations in the E6 or E7 open reading frame (ORF) replicated in C127 cells transformed by these mutants at a low copy number. Furthermore, the characterization of...

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Identifiers

PMID: 1321280
DOI: 10.1128/JVI.66.8.4957-4965.1992
PMCID: PMC241343

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