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Article

Identification and genetic definition of a bovine papillomavirus type 1 E7 protein and absence of a low-copy-number phenotype exhibited by E5, E6, or E7 viral mutants.

Journal of virology - 1 Aug 1992

Jareborg N, Alderborn A, Burnett S

Abstract excerpt

The bovine papillomavirus type 1 (BPV-1) genome replicates as a multiple-copy plasmid in murine C127 cells transformed to neoplasia by virus infection or by transfection with BPV-1 DNA. It was reported previously that BPV-1 genomes harboring frameshift mutations in the E6 or E7 open reading frame (ORF) replicated in C127 cells transformed by these mutants at a low copy number. Furthermore, the characterization of...

Topics

Animals
Blotting, Western
Bovine papillomavirus 1
Cell Line
Cell Transformation, Neoplastic
Genome, Viral
Mice
Molecular Weight
Oncogene Proteins, Viral
Papillomavirus E7 Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Restriction Mapping

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1321280
DOI: 10.1128/JVI.66.8.4957-4965.1992
PMCID: PMC241343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1321280-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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