Article
Solution structure of the activator contact domain of the RNA polymerase alpha subunit.
Science (New York, N.Y.) - 1 Dec 1995
Jeon Y H, Negishi T, Shirakawa M, Yamazaki T, Fujita N, Ishihama A, Kyogoku Y
Abstract excerpt
The structure of the carboxyl-terminal domain of the Escherichia coli RNA polymerase alpha subunit (alpha CTD), which is regarded as the contact site for transcription activator proteins and for the promoter UP element, was determined by nuclear magnetic resonance spectroscopy. Its compact structure of four helices and two long arms enclosing its hydrophobic core shows a folding topology distinct from those of...
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