Article
HLA-DQ associations in type 1 autoimmune hepatitis.
Mayo Clinic proceedings - 1 Dec 1995
Czaja A J, Santrach P J, Moore S B
Abstract excerpt
OBJECTIVE: To determine whether, in patients with type 1 autoimmune hepatitis and human leukocyte antigen (HLA) DR3 and DR4 positivity, any DQ antigen is disease-specific. MATERIAL AND METHODS: HLA class II typing was performed by restriction fragment length polymorphism in 103 patients with type 1 autoimmune hepatitis, 104 patients with chronic viral hepatitis, and 80 normal subjects. A shared association with a...
Topics
- Autoimmune Diseases
- Case-Control Studies
- Chronic Disease
- Female
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DR3 Antigen
- HLA-DR4 Antigen
- Haplotypes
