Article
The integrity of the cholecystokinin receptor gene in gallbladder disease and obesity.
Hepatology (Baltimore, Md.) - 1 Dec 1995
Nardone G, Ferber I A, Miller L J
Abstract excerpt
Cholesterol gallstone disease and obesity are common and often associated disorders that could be affected by dysfunction of the receptor for cholecystokinin (CCK). Extending earlier studies that identified a defect at the level of receptor-G protein coupling in cholesterol gallstone disease, we characterized the primary structure of the gallbladder CCK receptor in patients undergoing a cholecystectomy....
Topics
- Adult
- Aged
- Base Sequence
- Cholelithiasis
- Cholesterol
- DNA, Complementary
- Female
- GTP-Binding Proteins
- Gallbladder Diseases
- Humans
- Male
- Middle Aged