Article
Defects of androgen receptor function: from sex reversal to motor neurone disease.
Molecular and cellular endocrinology - 11 Aug 1995
MacLean H E, Warne G L, Zajac J D
Abstract excerpt
The androgen receptor (AR) is a ligand-dependent DNA transcription factor that binds androgens which cause masculinisation of the developing male fetus. Classical abnormalities of receptor function result in the syndrome of androgen resistance, with resultant failure of normal male differentiatio...
Topics
- Breast Neoplasms, Male
- Disorders of Sex Development
- Female
- Humans
- Infertility, Male
- Male
- Motor Neuron Disease
- Mutation
- Prostatic Neoplasms
- Receptors, Androgen