Article
Molecular basis of androgen insensitivity.
Steroids - 1 Apr 1996
Brinkmann A, Jenster G, Ris-Stalpers C, van der Korput H, Brüggenwirth H, Boehmer A, Trapman J
Abstract excerpt
Male sexual differentiation and development proceed under direct control of androgens. Androgen action is mediated by the intracellular androgen receptor, which belongs to the superfamily of ligand-dependent transcription factors. In the X-linked androgen insensitivity syndrome, defects in the an...
Topics
- Amino Acid Sequence
- Androgen-Insensitivity Syndrome
- Female
- Humans
- Male
- Molecular Sequence Data
- Motor Neuron Disease
- Muscular Atrophy, Spinal
- Mutation
- Receptors, Androgen
- Syndrome