Article
The clinical and molecular spectrum of androgen insensitivity syndromes.
American journal of medical genetics - 3 May 1996
Hiort O, Sinnecker G H, Holterhus P M, Nitsche E M, Kruse K
Abstract excerpt
Androgen insensitivity syndromes (AIS) are due to end-organ resistance to androgenic steroids in males leading to defective virilization of the external genitalia. The phenotype encompasses a wide array of genital ambiguity and may range from completely female to undervirilized but unequivocally male with infertility. This disorder is caused by mutations of the androgen receptor and is an X-linked recessive...
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