Article
Molecular genetics of androgen insensitivity syndromes.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 May 1994
Lobaccaro J M, Lumbroso S, Poujol N, Belon C, Sultan C
Abstract excerpt
The androgen receptor belongs to the family of nuclear receptors and contains three functional domains: a carboxy-terminal hormone binding region, a central cystein rich DNA binding region and an amino-terminal region involved in the expression of androgen regulated genes. Cloning of the complementary DNA encoding the androgen receptor enabled the characterization of the molecular defects associated with androgen...
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