Article
Molecular defects of the androgen receptor.
Recent progress in hormone research - 1 Jan 2002
McPhaul Michael J
Abstract excerpt
Mutations in the androgen receptor (AR) gene cause a range of phenotypic abnormalities of male sexual development. At one end of the spectrum are individuals with complete androgen insensitivity (complete testicular feminization) who exhibit normal breast development and female external genitalia. At the other extreme are individuals with male phenotypes that are characterized by either subtle undervirilization...
Topics
- Androgens
- Animals
- Cloning, Molecular
- Drug Resistance
- Humans
- Male
- Mutation
- Receptors, Androgen
