The plasticity of human telomeres demonstrated by a hypervariable telomere repeat array that is located on some copies of 16p and 16q.

doi:10.1093/hmg/8.9.1637

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Article

The plasticity of human telomeres demonstrated by a hypervariable telomere repeat array that is located on some copies of 16p and 16q.

Human molecular genetics - 1 Sept 1999

Coleman J, Baird D M, Royle N J

Abstract excerpt

Human telomeres are composed of tandem arrays of TTAGGG repeats with many variant repeats at the proximal ends. Comparison of the interspersion of variant and TTAGGG repeats between alleles can be used to study telomere instability, but the difficulty in identifying chromosome-specific sequences close to the start of autosomal telomeres has hampered such investigations. A chromosome end, including a telomere and...

Topics

Base Sequence
Blotting, Southern
Chromosomes, Human, Pair 16
Cloning, Molecular
Female
Genetic Linkage
Humans
Male
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Repetitive Sequences, Nucleic Acid

Sequence Alignment

Sequence Homology, Nucleic Acid

Telomere

White People

Source

Open in PubMed

Identifiers

PMID: 10441326
DOI: 10.1093/hmg/8.9.1637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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