Article
Sequences from higher primates orthologous to the human Xp/Yp telomere junction region reveal gross rearrangements and high levels of divergence.
Human molecular genetics - 1 Dec 1997
Baird D M, Royle N J
Abstract excerpt
A high level of sequence polymorphism combined with linkage disequilibrium has created a limited number of highly diverged haplotypes across the human Xp/Yp telomere junction region. To gain insight into the unusual genetic characteristics of this region, we have examined the orthologous sequence...
Topics
- Alleles
- Animals
- DNA, Satellite
- Evolution, Molecular
- Female
- Gorilla gorilla
- Haplotypes
- Humans
- Male
- Multigene Family
- Pan troglodytes
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Pongo pygmaeus
- Repetitive Sequences, Nucleic Acid
- Sequence Homology, Nucleic Acid
- Species Specificity
- Telomere