Article
Prp16p, Slu7p, and Prp8p interact with the 3' splice site in two distinct stages during the second catalytic step of pre-mRNA splicing.
RNA (New York, N.Y.) - 1 Aug 1995
Umen J G, Guthrie C
Abstract excerpt
For the second catalytic step of pre-mRNA splicing to occur, a 3' splice site must be selected and juxtaposed with the 5' exon. Four proteins, Prp16p, Slu7p, Prp17p, Prp18p, and an integral spliceosomal protein, Prp8p, are known to be required for the second catalytic step. prp8-101, an allele of...
Topics
- Adenosine Triphosphatases
- Binding Sites
- Cell Cycle Proteins
- DNA-Binding Proteins
- Fungal Proteins
- Mutation
- Nuclear Proteins
- RNA Helicases
- RNA Precursors
- RNA Splicing
- RNA Splicing Factors
- RNA, Messenger
- RNA-Binding Proteins
- Ribonucleoprotein, U4-U6 Small Nuclear
- Ribonucleoprotein, U5 Small Nuclear
- Ribonucleoproteins, Small Nuclear
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins