Vitamin D receptor genotypes in primary hyperparathyroidism.

doi:10.1038/nm1295-1309

Back to search

Article

Vitamin D receptor genotypes in primary hyperparathyroidism.

Nature medicine - 1 Dec 1995

Carling T, Kindmark A, Hellman P, Lundgren E, Ljunghall S, Rastad J, Akerström G, Melhus H

Abstract excerpt

Vitamin D and parathyroid hormone (PTH) constitute the main regulators of systemic calcium homeostasis. As well as its calcaemic effects, active vitamin D3(1,25(OH)2D3) has a direct regulatory role on parathyroid cells. Active vitamin D3 acts via its receptor (VDR), and binding of the ligand-rece...

Topics

Aged
Base Sequence
Calcitriol
DNA Primers
Female
Genotype
Humans
Hyperparathyroidism
Molecular Sequence Data
Parathyroid Glands
Parathyroid Hormone
Polymorphism, Genetic
Postmenopause
Receptors, Calcitriol

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.