Article
The vitamin D receptor (VDR) start codon polymorphism in primary hyperparathyroidism and parathyroid VDR messenger ribonucleic acid levels.
The Journal of clinical endocrinology and metabolism - 1 May 1999
Correa P, Rastad J, Schwarz P, Westin G, Kindmark A, Lundgren E, Akerström G, Carling T
Abstract excerpt
Vitamin D regulates parathyroid cell proliferation and secretion of PTH. Increased prevalence of the polymorphic vitamin D receptor (VDR) alleles b, a, and T has been reported in sporadic primary hyperparathyroidism (PHPT), suggesting that these genetic variants may predispose to the disease. Recently, another polymorphism in the VDR gene was related to bone mineral density, and this VDR-FokI polymorphism causes...
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