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Article

1,25-dihydroxyvitamin D and the vitamin D receptor gene polymorphism Apa1 influence bone mineral density in primary hyperparathyroidism.

PloS one - 1 Jan 2013

Christensen Monika H E, Apalset Ellen M, Nordbø Yngve, Varhaug Jan Erik, Mellgren Gunnar, Lien Ernst A

Abstract excerpt

OBJECTIVE: Parathyroid hormone (PTH) and vitamin D are the most important hormones regulating calcium metabolism. In primary hyperparathyroidism (PHPT) excessive amounts of PTH are produced. Bone turnover is enhanced, leading to reduced bone mineral density and elevated levels of serum calcium. The aim of this study was to investigate relations between serum levels of 25-hydroxyvitamin D (25(OH)D),...

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Source

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Identifiers

PMID: 23418495
DOI: 10.1371/journal.pone.0056019
PMCID: PMC3572149

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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