Article
Estrogen receptor gene polymorphism in postmenopausal primary hyperparathyroidism.
Surgery - 1 Dec 1997
Carling T, Rastad J, Kindmark A, Lundgren E, Ljunghall S, Akerström G
Abstract excerpt
BACKGROUND: Estrogen and its receptor play a key role in calcium homeostasis, with implications in both the development and treatment of primary hyperparathyroidism. METHODS: Leukocyte DNA was isolated from 101 postmenopausal female patients with primary hyperparathyroidism and age-matched female control subjects (n = 101). Polymorphic estrogen receptor alleles denoted P/p and X/x were detected by polymerase...
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